Can We Intercept Cancer? A New Frontier in Cancer Research Penn Medicine News News | Feb 28, 2023 Can we stop cancer before it starts? That’s part of the goal of cancer interception, which involves “catching” cancer cells as they begin to develop into pre-cancers or very early cancers, and halt or reverse that process. Latest News When Is It Time To Get Preventative Surgeries To Avoid Cancer? KJZZ News | October 2018 Basser Center Executive Director Susan Domchek, MD, joins KJZZ's The Show for an episode devoted to genetic testing, preventative surgery, and raising awareness of hereditary breast cancer. How Men Can Be Affected by the BRCA Gene, Too New York Post News | September 2018 Basser’s Susan Domchek, MD, and Penn Medicine patient Steven Merlin, whose participation in groundbreaking clinical trials using PARP inhibitor drugs has kept him cancer-free for six years, comment on how BRCA mutations affect men. With CRISPR, Scientists Engineered Nearly 4,000 Mutations of a Breast-Cancer Gene The Atlantic News | September 2018 Using CRISPR, a team assessed 3,893 otherwise unstudied mutations of BRCA1, which normally suppresses cancerous tumors, but can be rendered ineffective when they’re mutated. Centenarian Eagles Fan Becomes Social Media Star Jewish Exponent News | August 2018 The Basser family patriarch, Phil Basser, father to the Center's co-founder Mindy Gray and Basser Global Prize co-founder Shari Potter, is featured in the Jewish Exponent for his century of loving Philadelphia football. The club where no one has cancer — yet The Lily News | August 2018 Basser Young Leadership Council member Suzanne Zupello recently penned this personal piece on the importance of support communities for those with BRCA mutations for The Lily. At-Home DNA Tests are Changing How Patients See Themselves WHYY News | July 2018 WHYY's The Pulse sat down with Dana Clark, MS, LCGC, a genetic counselor in the Basser Center, to learn how these services are affecting decisions and outlooks on health. Free Panel to Explore Living with Inherited Cancer Risk The San Diego Tribune News | July 2018 The San Diego Union-Tribune reports on our upcoming panel on hereditary cancer and BRCA in La Jolla, California. Pilot Program Offers Free Genetic Testing for Ashkenazi Jews to Detect Cancer Risk Healio News | July 2018 Basser Executive Director, Susan Domchek, MD, explains the recently began BRCA Founder Outreach Study (BFOR) with the Cleveland Jewish News. Rucaparib Induces Response in BRCA-Mutated Pancreatic Cancer Healio News | July 2018 Basser Executive Director, Susan Domchek, MD, discusses the challenges of treating pancreatic cancer, the role of BRCA mutations in malignancies other than breast or ovarian cancers, and the broader role of PARP inhibitors for this patient population. Beyond BRCA: Examining Links between Breast Cancer, Second Primary Cancer and Inherited Genetic Mutations Penn Medicine News News | May 2018 Rates of inherited mutations in genes other than BRCA are twice as high in breast cancer patients who have had a second primary cancer – including, in some cases, different types of breast cancer – compared to patients who have only had a single breast cancer. Ovarian Cancer Drug Shows Promise in Pancreatic Cancer Patients with BRCA Mutation Penn Medicine News News | May 2018 A targeted therapy that has shown its power in fighting ovarian cancer in women, including those with BRCA1 and BRCA2 mutations, may also help patients with aggressive pancreatic cancer who harbor these mutations and have few or no other treatment options. The ‘Jolie Effect’ Was A Game-Changer For Breast Cancer, But It Was Just A Start Huffington Post News | May 2018 Basser Young Leadership Council Co-Chair Erika Stallings contributed this opinion piece to Huffington Post on the future of BRCA testing and on-going challenges, such as difficulties regarding access to genetic counseling and testing. Using Telemedicine to Bring Genetic Counseling to Community Cancer Care Penn Medicine News News | May 2018 Genetic counseling for cancer patients has become standard of care at academic medical centers. Video and phone sessions can bring genetic counseling to patients who would not otherwise have the chance to receive it, according to a new study from the Basser Center. Kravis, Ackman, and Gray Have Some Advice for New Philanthropists Bloomberg News | April 2018 Basser founders Mindy and Jon Gray are featured in a Bloomberg Markets article profiling people in finance who have defined their philanthropy early in their careers. PARP Drugs Help Some Breast Cancer Patients, But They’re No Magic Bullet Forbes News | April 2018 Forbes spoke with Susan Domchek, MD, Executive Director of the Basser Center, about how a woman with advanced breast cancer might choose among treatment options, and the latest data available on the effectiveness and safety of PARP inhibitors. PARP-1 May be Key to Effectiveness of PARP Inhibitors, and Now Researchers Can Image It Penn Medicine News News | April 2018 Penn Medicine researchers, including Basser's Roger Greenberg, PhD, MD, have used CRISPR/Cas9 gene editing technology to isolate a key genetic feature that could cause resistance to PARP inhibitors in patients with ovarian cancer. At-Home Genetic Testing May Be Convenient, but it Isn't Complete STAT News News | March 2018 In an op-ed about direct-to-consumer BRCA testing, Susan Domchek, MD, says that while genetic testing can be lifesaving, it must come with all the facts. F.D.A. Approves First Home Testing for 3 Breast Cancer Mutations, With Caveats New York Times News | March 2018 The FDA approved at-home genetic testing for BRCA mutations, while highlighting concerns. Susan Domchek, MD, cautioned that people may experience anxiety when undergoing genetic testing, and recommends that they discuss any concerns with their doctor. 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Can We Intercept Cancer? A New Frontier in Cancer Research Penn Medicine News News | Feb 28, 2023 Can we stop cancer before it starts? That’s part of the goal of cancer interception, which involves “catching” cancer cells as they begin to develop into pre-cancers or very early cancers, and halt or reverse that process.
When Is It Time To Get Preventative Surgeries To Avoid Cancer? KJZZ News | October 2018 Basser Center Executive Director Susan Domchek, MD, joins KJZZ's The Show for an episode devoted to genetic testing, preventative surgery, and raising awareness of hereditary breast cancer.
How Men Can Be Affected by the BRCA Gene, Too New York Post News | September 2018 Basser’s Susan Domchek, MD, and Penn Medicine patient Steven Merlin, whose participation in groundbreaking clinical trials using PARP inhibitor drugs has kept him cancer-free for six years, comment on how BRCA mutations affect men.
With CRISPR, Scientists Engineered Nearly 4,000 Mutations of a Breast-Cancer Gene The Atlantic News | September 2018 Using CRISPR, a team assessed 3,893 otherwise unstudied mutations of BRCA1, which normally suppresses cancerous tumors, but can be rendered ineffective when they’re mutated.
Centenarian Eagles Fan Becomes Social Media Star Jewish Exponent News | August 2018 The Basser family patriarch, Phil Basser, father to the Center's co-founder Mindy Gray and Basser Global Prize co-founder Shari Potter, is featured in the Jewish Exponent for his century of loving Philadelphia football.
The club where no one has cancer — yet The Lily News | August 2018 Basser Young Leadership Council member Suzanne Zupello recently penned this personal piece on the importance of support communities for those with BRCA mutations for The Lily.
At-Home DNA Tests are Changing How Patients See Themselves WHYY News | July 2018 WHYY's The Pulse sat down with Dana Clark, MS, LCGC, a genetic counselor in the Basser Center, to learn how these services are affecting decisions and outlooks on health.
Free Panel to Explore Living with Inherited Cancer Risk The San Diego Tribune News | July 2018 The San Diego Union-Tribune reports on our upcoming panel on hereditary cancer and BRCA in La Jolla, California.
Pilot Program Offers Free Genetic Testing for Ashkenazi Jews to Detect Cancer Risk Healio News | July 2018 Basser Executive Director, Susan Domchek, MD, explains the recently began BRCA Founder Outreach Study (BFOR) with the Cleveland Jewish News.
Rucaparib Induces Response in BRCA-Mutated Pancreatic Cancer Healio News | July 2018 Basser Executive Director, Susan Domchek, MD, discusses the challenges of treating pancreatic cancer, the role of BRCA mutations in malignancies other than breast or ovarian cancers, and the broader role of PARP inhibitors for this patient population.
Beyond BRCA: Examining Links between Breast Cancer, Second Primary Cancer and Inherited Genetic Mutations Penn Medicine News News | May 2018 Rates of inherited mutations in genes other than BRCA are twice as high in breast cancer patients who have had a second primary cancer – including, in some cases, different types of breast cancer – compared to patients who have only had a single breast cancer.
Ovarian Cancer Drug Shows Promise in Pancreatic Cancer Patients with BRCA Mutation Penn Medicine News News | May 2018 A targeted therapy that has shown its power in fighting ovarian cancer in women, including those with BRCA1 and BRCA2 mutations, may also help patients with aggressive pancreatic cancer who harbor these mutations and have few or no other treatment options.
The ‘Jolie Effect’ Was A Game-Changer For Breast Cancer, But It Was Just A Start Huffington Post News | May 2018 Basser Young Leadership Council Co-Chair Erika Stallings contributed this opinion piece to Huffington Post on the future of BRCA testing and on-going challenges, such as difficulties regarding access to genetic counseling and testing.
Using Telemedicine to Bring Genetic Counseling to Community Cancer Care Penn Medicine News News | May 2018 Genetic counseling for cancer patients has become standard of care at academic medical centers. Video and phone sessions can bring genetic counseling to patients who would not otherwise have the chance to receive it, according to a new study from the Basser Center.
Kravis, Ackman, and Gray Have Some Advice for New Philanthropists Bloomberg News | April 2018 Basser founders Mindy and Jon Gray are featured in a Bloomberg Markets article profiling people in finance who have defined their philanthropy early in their careers.
PARP Drugs Help Some Breast Cancer Patients, But They’re No Magic Bullet Forbes News | April 2018 Forbes spoke with Susan Domchek, MD, Executive Director of the Basser Center, about how a woman with advanced breast cancer might choose among treatment options, and the latest data available on the effectiveness and safety of PARP inhibitors.
PARP-1 May be Key to Effectiveness of PARP Inhibitors, and Now Researchers Can Image It Penn Medicine News News | April 2018 Penn Medicine researchers, including Basser's Roger Greenberg, PhD, MD, have used CRISPR/Cas9 gene editing technology to isolate a key genetic feature that could cause resistance to PARP inhibitors in patients with ovarian cancer.
At-Home Genetic Testing May Be Convenient, but it Isn't Complete STAT News News | March 2018 In an op-ed about direct-to-consumer BRCA testing, Susan Domchek, MD, says that while genetic testing can be lifesaving, it must come with all the facts.
F.D.A. Approves First Home Testing for 3 Breast Cancer Mutations, With Caveats New York Times News | March 2018 The FDA approved at-home genetic testing for BRCA mutations, while highlighting concerns. Susan Domchek, MD, cautioned that people may experience anxiety when undergoing genetic testing, and recommends that they discuss any concerns with their doctor.