Basser Center for BRCA Celebrates Breast Cancer Awareness Month TODAY News Susan Domchek, MD, executive director of the Basser Center, took part in a live interview on the TODAY Show with breast cancer survivor and Basser Advisory Board member Jill Martin. Latest News My Experience As a BRCA Mutation Carrier Very Well Health News | August 2021 Basser Young Leadership Council co-founder Erika Stallings shares the story of her BRCA journey with Very Well Health. Polygenic Risk Scores for Breast Cancer—Can They Deliver on the Promise of Precision Medicine? JAMA Network News | August 2021 A recently published JAMA Network study evaluated the use of polygenic risk scores (PRSs) models in a clinical setting for breast cancer risk among women of European, African, and Latino ancestry. Penn-led Consortium Identifies More Genetic Markers for Inherited Testicular Cancer Penn Medicine News News | July 2021 A meta-analysis of nearly 200,000 men revealed 22 new genetic locations that could be susceptible to inherited testicular germ cell tumors (TGCT) — a 40 percent increase in the number of regions known to be associated with the cancer. The multi-institutional meta-analysis was led by Basser Director of Genetics, Katherine L. Nathanson, MD. Black and White Women Have Same Mutations Linked to Breast Cancer Risk Penn Medicine News News | June 2021 The prevalence of genetic mutations associated with breast cancer in Black and white women is the same, according to a new JAMA Oncology study of nearly 30,000 patients led by Basser Center researchers. “The findings challenge past, smaller studies that found Black women face a greater genetic risk and the suggestion that race should be an independent factor when considering genetic testing,” said first author Susan Domchek, MD, Basser Execute Director. 34 ASCO Members Receive Fellows Distinction Healio News | June 2021 Basser Executive Director Susan Domchek, MD, received a Fellow of the American Society of Clinical Oncology distinction at the American Society of Clinical Oncology annual meeting. The honor recognizes ASCO members’ extraordinary volunteer service, dedication, and commitment to the society. AstraZeneca drug prevents breast cancer caused by BRCA mutations from returning Stat News News | June 2021 Findings to be presented during a plenary session at the American Society of Clinical Oncology meeting show that a PARP inhibitor significantly reduced the risk that breast cancer would return when given to patients with the BRCA mutation. Basser Executive Director Susan Domchek, MD, serves as lead investigator of the Penn trial. Breast Cancer Leads Latinas' Cancer Deaths Axois News | June 2021 Susan Domchek, MD, Basser Executive Director, was featured in a story about Latinas and BRCA mutations. Despite the high prevalence of the mutations, awareness of hereditary cancer risks and genetic testing is low among this group, limiting their options for early treatment, she said. A Break from Chemo: PARP Inhibitor Shrinks Tumors in Pancreatic Cancer Patients with Mutations Penn Medicine News News | May 2021 Many pancreatic cancer patients with BRCA and PALB2 mutations saw their tumors stop growing or shrink substantially after being switched from chemotherapy to the PARP inhibitor rucaparib, according to results from a clinical trial led by Basser Center researchers. DNA Testing Sets Up a Stark Medical Decision Washington Post News | April 2021 Susan Domchek, MD, Basser Center Executive Director, was quoted in a Wall Street Journal article that profiled a woman’s experience with genetic testing and a surprising family tree that led her to make decisions about her cancer care. Racial disparities still persist in genetic testing for BRCA-related breast cancer Philly Voice News | April 2021 Philly Voice highlights our Black & BRCA initiative, which launched last fall to help raise awareness about genetic testing in the Black community. Next-Generation Sequencing Informs Genetic Testing in Breast Cancer Targeted Oncology News | March 2021 Susan Domchek, MD, Executive Director of the Basser Center, was quoted in a story about the growing understanding of genetic risk factors for breast cancer and the ongoing debate on recommendations for genetic testing. Race Has No Place in Precision Oncology Med Page Today News | March 2021 In an op-ed, Basser Director of Genetics Katherine L. Nathanson, MD, joined other Penn physicians in offering strategies to “nudge” oncologists to overcome race as a heuristic in decision-making. Hot Topics in Pancreatic Cancer with Kim Reiss Binder Healio News | March 2021 Basser researcher Kim Reiss Binder, MD, was featured in a series of videos on the latest in pancreatic cancer research and therapies, discussing immunotherapies, early detection, and metastatic disease. Ambiguous Genetic Test Results Can Be Unsettling. Worse, They Can Lead to Needless Surgeries Washington Post News | February 2021 Basser Executive Director Susan Domchek, MD, was quoted in a story on the ambiguity of certain genetic tests and how “variants of unknown significance” (VUS) can guide cancer treatments, despite a lack of evidence to support those decisions. Mutations Commonly Linked to Breast Cancer Found to Pose No Increased Risk, Population Study Reveals Penn Medicine News News | January 2021 Several genetic mutations previously linked to breast cancer and included on commercial genetic tests were found not to increase a woman’s risk of disease, according to a population study published today in the New England Journal of Medicine, involving the Basser Center and Penn Medicine. ALC1 Links Chromatin Accessibility to PARP Inhibitor Response in Homologous Recombination-Deficient Cells Nature Cell Biology News | January 2021 Researchers led by Basser Director of Basic Science Roger Greenberg, MD, PhD, found that eliminating an enzyme called ALC1 can potentially increasing the effectiveness of PARP inhibitors in cancer treatment. 10 Cancer Super Survivors You Need to Follow on Instagram Right Now Parade News | December 2020 This helpful list of cancer survivors to follow on Instagram includes Alejandra Campoverdi, our partner on LATINX & BRCA. Everviolet Chats: Erika Stallings Everviolet News | December 2020 Everviolet talked to Basser Young Leadership Council co-chair Erika Stallings about her experience with BRCA and hereditary cancer. Pagination First page« First Previous page‹‹ … Page3 Page4 Page5 Page6 Current page7 Page8 Page9 Page10 Page11 … Next page›› Last pageLast »
Basser Center for BRCA Celebrates Breast Cancer Awareness Month TODAY News Susan Domchek, MD, executive director of the Basser Center, took part in a live interview on the TODAY Show with breast cancer survivor and Basser Advisory Board member Jill Martin.
My Experience As a BRCA Mutation Carrier Very Well Health News | August 2021 Basser Young Leadership Council co-founder Erika Stallings shares the story of her BRCA journey with Very Well Health.
Polygenic Risk Scores for Breast Cancer—Can They Deliver on the Promise of Precision Medicine? JAMA Network News | August 2021 A recently published JAMA Network study evaluated the use of polygenic risk scores (PRSs) models in a clinical setting for breast cancer risk among women of European, African, and Latino ancestry.
Penn-led Consortium Identifies More Genetic Markers for Inherited Testicular Cancer Penn Medicine News News | July 2021 A meta-analysis of nearly 200,000 men revealed 22 new genetic locations that could be susceptible to inherited testicular germ cell tumors (TGCT) — a 40 percent increase in the number of regions known to be associated with the cancer. The multi-institutional meta-analysis was led by Basser Director of Genetics, Katherine L. Nathanson, MD.
Black and White Women Have Same Mutations Linked to Breast Cancer Risk Penn Medicine News News | June 2021 The prevalence of genetic mutations associated with breast cancer in Black and white women is the same, according to a new JAMA Oncology study of nearly 30,000 patients led by Basser Center researchers. “The findings challenge past, smaller studies that found Black women face a greater genetic risk and the suggestion that race should be an independent factor when considering genetic testing,” said first author Susan Domchek, MD, Basser Execute Director.
34 ASCO Members Receive Fellows Distinction Healio News | June 2021 Basser Executive Director Susan Domchek, MD, received a Fellow of the American Society of Clinical Oncology distinction at the American Society of Clinical Oncology annual meeting. The honor recognizes ASCO members’ extraordinary volunteer service, dedication, and commitment to the society.
AstraZeneca drug prevents breast cancer caused by BRCA mutations from returning Stat News News | June 2021 Findings to be presented during a plenary session at the American Society of Clinical Oncology meeting show that a PARP inhibitor significantly reduced the risk that breast cancer would return when given to patients with the BRCA mutation. Basser Executive Director Susan Domchek, MD, serves as lead investigator of the Penn trial.
Breast Cancer Leads Latinas' Cancer Deaths Axois News | June 2021 Susan Domchek, MD, Basser Executive Director, was featured in a story about Latinas and BRCA mutations. Despite the high prevalence of the mutations, awareness of hereditary cancer risks and genetic testing is low among this group, limiting their options for early treatment, she said.
A Break from Chemo: PARP Inhibitor Shrinks Tumors in Pancreatic Cancer Patients with Mutations Penn Medicine News News | May 2021 Many pancreatic cancer patients with BRCA and PALB2 mutations saw their tumors stop growing or shrink substantially after being switched from chemotherapy to the PARP inhibitor rucaparib, according to results from a clinical trial led by Basser Center researchers.
DNA Testing Sets Up a Stark Medical Decision Washington Post News | April 2021 Susan Domchek, MD, Basser Center Executive Director, was quoted in a Wall Street Journal article that profiled a woman’s experience with genetic testing and a surprising family tree that led her to make decisions about her cancer care.
Racial disparities still persist in genetic testing for BRCA-related breast cancer Philly Voice News | April 2021 Philly Voice highlights our Black & BRCA initiative, which launched last fall to help raise awareness about genetic testing in the Black community.
Next-Generation Sequencing Informs Genetic Testing in Breast Cancer Targeted Oncology News | March 2021 Susan Domchek, MD, Executive Director of the Basser Center, was quoted in a story about the growing understanding of genetic risk factors for breast cancer and the ongoing debate on recommendations for genetic testing.
Race Has No Place in Precision Oncology Med Page Today News | March 2021 In an op-ed, Basser Director of Genetics Katherine L. Nathanson, MD, joined other Penn physicians in offering strategies to “nudge” oncologists to overcome race as a heuristic in decision-making.
Hot Topics in Pancreatic Cancer with Kim Reiss Binder Healio News | March 2021 Basser researcher Kim Reiss Binder, MD, was featured in a series of videos on the latest in pancreatic cancer research and therapies, discussing immunotherapies, early detection, and metastatic disease.
Ambiguous Genetic Test Results Can Be Unsettling. Worse, They Can Lead to Needless Surgeries Washington Post News | February 2021 Basser Executive Director Susan Domchek, MD, was quoted in a story on the ambiguity of certain genetic tests and how “variants of unknown significance” (VUS) can guide cancer treatments, despite a lack of evidence to support those decisions.
Mutations Commonly Linked to Breast Cancer Found to Pose No Increased Risk, Population Study Reveals Penn Medicine News News | January 2021 Several genetic mutations previously linked to breast cancer and included on commercial genetic tests were found not to increase a woman’s risk of disease, according to a population study published today in the New England Journal of Medicine, involving the Basser Center and Penn Medicine.
ALC1 Links Chromatin Accessibility to PARP Inhibitor Response in Homologous Recombination-Deficient Cells Nature Cell Biology News | January 2021 Researchers led by Basser Director of Basic Science Roger Greenberg, MD, PhD, found that eliminating an enzyme called ALC1 can potentially increasing the effectiveness of PARP inhibitors in cancer treatment.
10 Cancer Super Survivors You Need to Follow on Instagram Right Now Parade News | December 2020 This helpful list of cancer survivors to follow on Instagram includes Alejandra Campoverdi, our partner on LATINX & BRCA.
Everviolet Chats: Erika Stallings Everviolet News | December 2020 Everviolet talked to Basser Young Leadership Council co-chair Erika Stallings about her experience with BRCA and hereditary cancer.