1 in 7 women with ovarian cancer have a BRCA mutation

Improving Early Detection and Treatment Options for Ovarian Cancer

Improving early detection and treatment of ovarian cancer is an important area of focus for the Basser Center for BRCA. Read about the latest research and ongoing studies focusing on screening, preventative surgery, and treatment options for ovarian cancer.

COVID-19 Resources

View Basser Center and Penn Medicine resources on the COVID-19 pandemic, particularly geared towards cancer patients and BRCA mutation carriers.

BRCA and Melanoma

Melanoma is a rare form of skin cancer that only makes up 1% of overall skin cancers. However, it is a particularly aggressive form, which it is why it’s important to recognize symptoms and know your personal risk for melanoma.

B is for Bravery: A BRCA War Story 

Basser Young Leadership Council member Callum Beale writes about his sister's ongoing battle with BRCA-related cancer and how he is inspired by her bravery.

Telehealth Considerations

Basser Center genetic counselor Jacquelyn Powers, MS, LCGC, writes about her experience seeing patients via telehealth and considerations for the future.

Genetic Counseling via Telehealth

Basser Center genetic counselor Jacquelyn Powers, MS, LCGC, discusses genetic counseling via telehealth and what patients can expect from a typical appointment.

Considerations for “Previvors” During COVID-19

The Basser Center understands that for BRCA1 and BRCA2 mutation carriers and others at high risk of cancer, COVID-19 may have disrupted screening schedules and surgical plans. While each situation is unique, we offer the following general advice.

Maria Malloy

Advice from a Nurse Navigator: What to Expect from a Breast Cancer Diagnosis

Maria Malloy, BSN, RN, OCN, CBCN, a nurse navigator in Penn Medicine’s Breast Cancer program, discusses what to expect from a breast cancer diagnosis.


Finding Support and Community Through Instagram: A Conversation with Mackenzie Alleman

Mackenzie Alleman, a BRCA mutation carrier and patient advocates, shares how she found support and community online and offers suggestions to those looking for help.

Jamila Kinsey with her mother and sister

Raising Awareness of Breast Cancer in the Black Community: A Discussion with Jamila Kinsey

Jamila Kinsey, a BRCA mutation carrier and patient advocate talks about the importance of raising awareness of breast cancer in the Black community and why this is so vital.

Genetic Counselor Takeover: Genetic Counseling as a Route to Genetic Evaluation (and Beyond)

Jessica M. Long, MS, LCGC, a genetic counselor at the Basser Center, writes about the importance of genetic counseling, potential obstacles to meeting a counselor in person, and remote options.

Navigating Sexual Health and Intimacy After Surgery: A Discussion with Dana Donofree

Dana Donofree, designer and founder of AnaOno Intimages, shares her own experience with cancer and discusses how to navigate sexual health and intimacy after surgery.

Penn Center for Genome Integrity: Hereditary Cancer and Beyond

Roger Greenberg, MD, PhD, the Basser Center’s Director of Basic Science and the Director of the new Penn Center for Genome Integrity, discusses the new Center and how its research will apply to hereditary cancer and more.

Genetic Counselor Takeover: Direct-to-Consumer Genetic Testing for Hereditary Cancer Risk

Basser Center genetic counselor Jessica M. Long, MS, LCGC, explains the ins and outs of direct-to-consumer genetic testing for hereditary cancer risk.

Ask Dr. Domchek: Enhancing PARP Inhibitors

As part of an ongoing series of answers to common questions received by the Basser Center, Executive Director Susan Domchek, MD, discusses PARP inhibitors and ways in which they might be combined with other cancer treatments.

Changes in Classification of BRCA1/2 Mutations are Extremely Rare

In light of a recent news article, the Basser Center stresses that it is extremely rare that genetic testing reports change an interpretation from harmful to anything less than that. If you have been told that you have a BRCA mutation, it is exceedingly unlikely that anything has changed.

Genetic Counselor Takeover: What Age Should You be Tested for a BRCA Mutation?

Basser Center genetic counselors Danielle McKenna, MS, LCGC, explains what age at which at-risk individuals should consider testing for a BRCA mutation.

Prostate Cancer Screening with a BRCA Mutation

Kara Maxwell, MD, PhD, a physician scientist with the Basser Center and University of Pennsylvania, discusses hereditary prostate cancer and recent scientific advancements.