Latest News
Ovarian tumor scan

PARP-1 May be Key to Effectiveness of PARP Inhibitors, and Now Researchers Can Image It

Penn Medicine News

Penn Medicine researchers, including Basser's Roger Greenberg, PhD, MD, have used CRISPR/Cas9 gene editing technology to isolate a key genetic feature that could cause resistance to PARP inhibitors in patients with ovarian cancer.

Stomach ache

Many Women Mistake Common Symptom of Ovarian Cancer for Indigestion

Healthline

Healthline reports on recent research showing that many women who experience a bloating feeling on a regular basis are more likely to change their diets than visit their doctors, and in some cases, that could put women at risk of overlooking ovarian cancer symptoms. 

The Role of Biomarkers in Patients with Breast Cancer

Targeted Oncology

Susan M. Domchek, MD, Executive Director of the Basser Center for BRCA, discusses the role biomarkers have in the treatment of patients with breast cancer. Identifying biomarkers in patients early on, such as knowledge of estrogen receptor status, can lead to better treatment plans, Domchek says.

When it comes to home cancer tests, think before you spit

USA Today

U.S. consumers soon will be able to test themselves at home for some genetic mutations that increase the risk of breast, ovarian and prostate cancer — but you might want to think before you spit. Susan Domchek, MD, speaks to USA Today about BRCA mutations.

Genetic testing

At-Home Genetic Testing May Be Convenient, but it Isn't Complete

STAT News

In an op-ed about direct-to-consumer BRCA testing, Susan Domchek, MD, says that while genetic testing can be lifesaving, it must come with all the facts. 

Illustration

Relearning How to Date After My Double Mastectomy

The Cut

Basser Young Leadership Council co-chair Erika Stalings reveals her experiences with dating after undergoing a preventive double mastectomy, and her struggles to decide if and when to tell dates about the surgery and her BRCA mutation status.

Think Before Trying Home Breast Cancer Gene Tests, Experts Urge

USA Today

Genetic counselors, oncologists and other experts are urging consumers to do their homework before sending in saliva samples and allowing their DNA to be screened for certain cancer risks by the company 23andMe.

DNA

Genetic Study Makes Testing More Accessible

Jewish Exponent

The BRCA Founder Outreach (BFOR) study, focusing on individuals of Ashkenazi descent, will give participants the opportunity to receive simpler access to genetic testing.

Exam

F.D.A. Approves First Home Testing for 3 Breast Cancer Mutations, With Caveats

New York Times

The FDA approved at-home genetic testing for BRCA mutations, while highlighting concerns. Susan Domchek, MD, cautioned that people may experience anxiety when undergoing genetic testing, and recommends that they discuss any concerns with their doctor.

Cancer imaging

BRCA Breast Cancer Patients Finally Have a Non-Chemotherapy Treatment Option

Genome

The FDA approved the first oral treatment for breast cancer patients who have inherited mutations in their BRCA genes. Susan Domchek, MD, who was involved in the clinical trial, discusses how this is a major step forward.

Painting of the Basser family

Faith, Fate, and Families

Penn Medicine Magazine

Penn Medicine Magazine's latest issue includes the story of how the Basser Center was founded in memory of Faith Basser, and how BRCA mutations can impact families around the world.

Expert Discusses Promise of Olaparib/Durvalumab Combo in BRCA+ Breast Cancer

Targeted Oncology

Susan Domchek, MD, Executive Director of the Basser Center, discussed the evolving treatment landscape for patients with BRCA-related, metastatic breast cancer.

Phil Basser Celebrates 100 Years with the Eagles

Fox News

Basser Center co-founder Mindy Gray's family is in the news, thanks to her inspiring father, Phil Basser, whose love of the Eagles has gone viral just before his 100th birthday. 

Susan Domchek

Breast Cancer Caused by Genetic Mutation Gets First Approved Treatment Through FDA Approval of Olaparib

Philadelphia Inquirer

The U.S. Food and Drug Administration recently approved olaparib as the first treatment for advanced breast cancer caused by mutations in BRCA genes, in an important step in the fight against inherited cancers. 

Individual Knowledge Is Power in Addressing BRCA Gene Mutations

Cure Magazine

Last week, journalist Joan Lunden moderated a panel of experts, “Knowledge is Power: Understanding and Managing BRCA-Related Cancer Risk.” The program, co-presented by the Basser Center, focused on the latest lifesaving information surrounding BRCA-related cancers.

Olaparib/Durvalumab Combo Effective for BRCA-mutant Breast Cancer

OncLive

OncLive reports on recent Penn-led research showing that the combination of olaparib and durvalumab demonstrated a disease control rate of 80 percent for pretreated patients with germline BRCA-mutated, HER2- negative metastatic breast cancer. 

For Cancer Survivor, the Bell Tolls Loudly

Bloomberg

The biennial Basser Jean Bash celebrated five years of progress toward understanding, treating and preventing hereditary cancers. The benefit honored Raquel and Michael Hass and Pulitzer Prize-winning author Siddhartha Mukherjee, MD, DPhil.

Can Telomere Length Reveal How Well You’re Aging?

Good Morning America

TeloYears is an at-home test that promises to reveal a user's true biological age by measuring telomeres, the ends of chromosomes that wear down over time. Susan Domchek, MD, advised caution, saying there has to be more study.